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readme.thrgibbs1 [2012/05/29 13:18] shogoreadme.thrgibbs1 [2013/12/19 16:38] ignacy
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-====== ACCF90 ====== +====== THRGIBBS1F90 ======
-\\ +
-Gibbs sampler for threshold-linear mixed models+
  
 =====Summary===== =====Summary=====
- +Gibbs sampler for threshold-linear mixed models. The original program (THRGIBBSF90) was written by DeukHwan Lee in 2001 based on GIBBS2F90 and formulas by Rob Tempelman. Rewritten by Shogo Tsuruta in 2004. See PREGSF90 with genotypes (SNP) for options. 
-Based on THRGIBBSF90 written by DeukHwan Lee at the University of Georgia, 2001 based on GIBBS2F90. Rewritten by Shogo Tsuruta2004. Last modified 09/05/2007 +\\
- +
- +
-=====Functionality=====+
 THRGIBBS1F90 implements Gibbs sampler for mixed threshold-linear models involving multiple categorical and linear variables. Thresholds and variances can be estimated or assumed. Another version of thrgibbs1f90b for binary responses is available. THRGIBBS1F90 implements Gibbs sampler for mixed threshold-linear models involving multiple categorical and linear variables. Thresholds and variances can be estimated or assumed. Another version of thrgibbs1f90b for binary responses is available.
 +\\
 +See PREGSF90 with genotypes (SNP) for options.
  
 =====Parameters===== =====Parameters=====
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 OPTION solution all OPTION solution all
 </file> </file>
-Store all samples for solutions in "all_solutions" and posterior means and SD for all effects.+Store all samples for solutions in "all_solutions" and posterior means and SD for all effects. The file "all_solutions" could be very large.
 <file> <file>
 OPTION solution all 1 2 3 OPTION solution all 1 2 3
 </file> </file>
-Store all samples for solutions in "all_solutions" and posterior means and SD for 1, 2, and 3 effects.+Store all samples for solutions in "all_solutions" and posterior means and SD for 1, 2, and 3 effects. The file "all_solutions" could be very large.
 <file> <file>
 OPTION solution mean OPTION solution mean
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 OPTION cont 10000 OPTION cont 10000
 </file> </file>
-"10000" is the number of samples run previously. +"10000" is the number of samples run previously. The user can restart the program from the last run.
-The user can restart the program from the last run.+
 <file> <file>
-OPTION prior 5+OPTION prior 5 2 -1 
 </file> </file>
-"5" is the degree of belief for the priors specified in the parameter file.+The (co)variance  priors are specified in the parameter file.\\ 
 +Degree of belief for all random effects should be specified using the following structure:\\ 
 +OPTION prior eff1 db1    eff2 db2 ...    effn dbn    -1 dbres\\ 
 +effx correspond to the effect number and dbx to the degree of belief for this random effect, -1 corresponds to the degree of belief of the residual variance.\\ 
 +In this example 2 is the degree of belief for the 5th effect, and 5 is the degree of belief for the residual.\\
 <file> <file>
 OPTION seed 123 -432 OPTION seed 123 -432
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 OPTION thresholds 0.0 1.0 2.0 OPTION thresholds 0.0 1.0 2.0
 </file> </file>
-Set the fixed thresholds. No need to set 0 for binary traits+Set the fixed thresholds. No need to set 0 for binary traits.
 <file> <file>
-OPTION residual 1+OPTION residual 1.
 </file> </file>
-Set the residual variance = 1+Set the residual variance = 1.
 <file> <file>
-OPTION censored xx+OPTION censored xx.
 </file> </file>
 Negative values of the last category in the data set indicate censored records. "xx" determines the lower and upper limit of the category + xx when sampling from the distribution. Negative values of the last category in the data set indicate censored records. "xx" determines the lower and upper limit of the category + xx when sampling from the distribution.
- +OPTION SNP_file snp 
 +</file> 
 +Specify the SNP file name to use genotype data.
readme.thrgibbs1.txt · Last modified: 2024/03/25 18:22 by 127.0.0.1

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